In rare cases, gastrointestinal side effects from Ozempicincluding nausea, vomiting, and diarrhoeacan lead to dehydration, which may temporarily affect kidney function markers and electrolyte levels
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In a Phase II study reported in 2024 involving 168 patients with NASH, moderate to advanced fibrosis (F2F3), and NAS 4, a significantly greater proportion of patients in the denifanstat group achieved the primary endpoint compared with placebo, with statistically meaningful improvements in fibrosis as well
J Endocrinol Invest 2017;40:12511258
The remaining authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article